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Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death

by Sudhish Sharma | Jun 5, 2014 | Journals, Uncategorized

Abstract Protein homeostatic regulators have been shown toameliorate single, loss-of-function protein diseases but not totreat broader animal disease models that may involve celldeath. Diseases often trigger protein homeostatic instabilitythat disrupts the delicate...

A Strong Regenerative Ability of Cardiac Stem Cells Derived From Neonatal Hearts

by Sudhish Sharma | Sep 11, 2012 | Journals, Uncategorized

Abstract Background—Human stem cells (CSCs) promote myocardial regeneration in adult ischemic myocardium. The regenerative capacity of CSCs in the very young patients with non-ischemic congenital heart defects has not been explored. We hypothesized that isolated...

Characterization and Functionality of Cardiac Progenitor Cells in Congenital Heart Patients

by Sudhish Sharma | Feb 1, 2011 | Journals, Uncategorized

Abstract Background—Human cardiac progenitor cells (hCPCs) may promote myocardial regenerationin adult ischemic myocardium. The regenerative capacity of hCPCs in young patients withnonischemic congenital heart defects for potential use in congenital heart defect...
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Recent Posts

  • NeoProgen receives approval from U.S. FDA for a Phase I Study of The Safety And Early Efficacy of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) In Chronic Ischemic Heart Failure
  • NeoProgen, Inc. Receives First Granted Patent for Method to Treat Cardiac Conditions using Neonatal Heart-derived Medicinal Signaling Cells (nMSCs) and/or their Secretomes/Exosomes from the US Patent Office
  • Secretome Therapeutics Presents Scientific Poster on the Essential Role of Complete Secretome in Regenerative Cell Therapy at ISSCR 2023 Annual Meeting
  • Secretome Therapeutics Announces Appointment of Angela Shen, M.D., M.B.A., to Board of Directors
  • Comparative efficacy and mechanism of action of cardiac progenitor cells after cardiac injury
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