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Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death

by Sudhish Sharma | Jun 5, 2014 | Journals, Uncategorized

Abstract Protein homeostatic regulators have been shown toameliorate single, loss-of-function protein diseases but not totreat broader animal disease models that may involve celldeath. Diseases often trigger protein homeostatic instabilitythat disrupts the delicate...

A Strong Regenerative Ability of Cardiac Stem Cells Derived From Neonatal Hearts

by Sudhish Sharma | Sep 11, 2012 | Journals, Uncategorized

Abstract Background—Human stem cells (CSCs) promote myocardial regeneration in adult ischemic myocardium. The regenerative capacity of CSCs in the very young patients with non-ischemic congenital heart defects has not been explored. We hypothesized that isolated...

Characterization and Functionality of Cardiac Progenitor Cells in Congenital Heart Patients

by Sudhish Sharma | Feb 1, 2011 | Journals, Uncategorized

Abstract Background—Human cardiac progenitor cells (hCPCs) may promote myocardial regenerationin adult ischemic myocardium. The regenerative capacity of hCPCs in young patients withnonischemic congenital heart defects for potential use in congenital heart defect...
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Recent Posts

  • Secretome Therapeutics Appoints Dr. Marshelle Smith Warren as Chief Medical Officer
  • Secretome Therapeutics Announces First Patient Dosed in Groundbreaking Phase 1 Study of STM-01 in Heart Failure with Preserved Ejection Fraction
  • Secretome Therapeutics Granted FDA Fast Track Designation for STM-01, a Neonatal Cardiac Progenitor Cell Therapy for HFpEF
  • Cellipont Bioservices and Secretome Therapeutics Partner for cGMP Manufacturing for Master Cell Bank for Lead Asset STM-01
  • Secretome Therapeutics Closes $20.4 Million Financing Round to Advance Cardiomyopathy and Heart Failure Therapies
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