Publications
Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death
Abstract Protein homeostatic regulators have been shown toameliorate single, loss-of-function protein diseases but not totreat broader animal disease models that may involve celldeath. Diseases often trigger protein homeostatic instabilitythat disrupts the delicate...
A Strong Regenerative Ability of Cardiac Stem Cells Derived From Neonatal Hearts
Abstract Background—Human stem cells (CSCs) promote myocardial regeneration in adult ischemic myocardium. The regenerative capacity of CSCs in the very young patients with non-ischemic congenital heart defects has not been explored. We hypothesized that isolated...
Characterization and Functionality of Cardiac Progenitor Cells in Congenital Heart Patients
Abstract Background—Human cardiac progenitor cells (hCPCs) may promote myocardial regenerationin adult ischemic myocardium. The regenerative capacity of hCPCs in young patients withnonischemic congenital heart defects for potential use in congenital heart defect...